Routinely referred to as "the most expensive street in the world," Manhattan's major thoroughfare Fifth Avenue is an iconic New York destination. From Greenwich Village to Central Park to the Museum Mile and Harlem, Fifth Avenue holds some of New Yorks most important historical, cultural, and, yes, commercial places. If, like most people, you can't afford to splurge at stores like Saks, you can still visit the Metropolitan Museum of Art or the landmark 500 Fifth Avenue.